When to see a doctor

If your doctor discovers high blood protein during an evaluation, he or she may recommend additional tests to determine if there is an underlying problem.

A total protein test can determine whether you have high blood protein. Other more-specific tests, including serum protein electrophoresis (SPEP), can help determine the exact source, such as liver or bone marrow, as well as the specific protein type involved in your high blood protein levels. Your doctor may order an SPEP if he or she suspects you have a bone marrow disease.